I gave this a try and it made the picture viewer app very unhappy.. slow scrolling, slow response to various inputs, and the long-press menu - when it finally appeared - would show up totally blank (although if I guessed at where the commands were supposed to be, it would perform the correct action). The behaviour persisted across restarts as well.

I also noticed a few other graphical oddities around the UI that weren't working the way they should have been... I reverted hildon_desktop.ini to default and everything is working the way it should again, so that tweak was definitely the culprit in my case.

Too bad, because it really did make some of the animations (desktop swiping most noticeably) incredibly smooth.