USB's bad, for sure, and power is unfortunate; the audio plug, though, is above where my hand goes when two-thumbing. And the audio should be in one end for convenience when pocketing with a headset; the power and USB could be relocated to better places, though. (And I'd have liked the audio on the same end as the d-pad, for playback control, but now I use BT anyway...)

(I more frequently one-finger, FWIW; holding the left hand-through-stand, thumb on d-pad, and running right hand up and down the long axis of the screen like a gantry and picking out letters with my index finger is almost as fast as thumbing, and more convenient to transition pointing <--> typing.)

And if I was in a part of town where I was concerned about the N800 being ripped out of my hands, I think I'd rather have my fingers through brass knuckles than the kickstand.